Protein Engineering Design and Selection - recent issues
Sun Apr 24 04:39:07 EDT 2011
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Importance of an extreme C-terminal motif of a family I.3 lipase for stability

Conversion of scFv peptide-binding specificity for crystal chaperone development

Modulating the pH-activity profile of cellulase A from Cellulomonas fimi by replacement of surface residues

Changing the substrate specificity of P450cam towards diphenylmethane by semi-rational enzyme engineering

Therapeutic assessment of SEED: a new engineered antibody platform designed to generate mono- and bispecific antibodies

Can computationally designed protein sequences improve secondary structure prediction?

Engineered dimer interface mutants of triosephosphate isomerase: the role of inter-subunit interactions in enzyme function and stability

Dynamics studies of luciferase using elastic network model: how the sequence distribution of luciferase determines its color

Epitope mapping and key amino acid identification of anti-CD22 immunotoxin CAT-8015 using hybrid {beta}-lactamase display

Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors

Interleukin-15:Interleukin-15 receptor {alpha} scaffold for creation of multivalent targeted immune molecules

Combining phage and staphylococcal surface display for generation of ErbB3-specific Affibody molecules

Detecting structural similarity of ligand interactions in the lipid metabolic system including enzymes, lipid-binding proteins and nuclear receptors

A geometry-based generic predictor for catalytic and allosteric sites

Recombinant botulinum neurotoxin A heavy chain-based delivery vehicles for neuronal cell targeting

GPS 2.1: enhanced prediction of kinase-specific phosphorylation sites with an algorithm of motif length selection

Surface supercharged human enteropeptidase light chain shows improved solubility and refolding yield

High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine

Computational design of the lasso peptide antibiotic microcin J25

Evolution of interleukin-15 for higher E. coli expression and solubility

A novel sequence-based antigenic distance measure for H1N1, with application to vaccine effectiveness and the selection of vaccine strains

Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes

Construction and maintenance of randomized retroviral expression libraries for transmembrane protein engineering

Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin

The identification of novel cyclic AMP-dependent protein kinase anchoring proteins using bioinformatic filters and peptide arrays