Gynecologic Cancer Forum: Online Information & Resources
Sun Apr 24 04:15:41 EDT 2011
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GCT convention - Hi anyone that attended the GCT convention in Boston, please, let us know what you learned.  I'm having a reacurrence of GCT and am using maintenance of Avastin and Taxal.  So far I think its working to keep my tumors at bay.  In a couple of months I will have a ct scan to see.  I'm also using flaxseed oil with organic yoghurt and beta/glucan and CoQ10 and probiotic and enzymes.  The test show I'm low on magnesium so I'm on 5 400mgs of magnesium oxide, but it isn 't bringing my level up.  If you have any answers about how to bring it up I would greatly appreciate it.  Ann

Leep procedure - Hey looking for anybody who has been through this. Was diagnosed with severe cervical dysplasia. 3 weeks ago I had a leep done which was under local Anesthetic. It was't what I wanted to be doing on a Tuesday but the doctor did the colposcopy and then did the leep. It was'nt bad at all watched the whole procedure being done on the screen. While getting it done talked about general stuff with the nurses and the doctor. Bleed a little but the thing that annoyed me the most was having to wear pads. Yeah I know better things to be worried about. So I thought was done and dusted. Appointment for 6 months later and told give up smoking. Yeah I know for the puritans out there, stupid habit to have. Have booked myself in to do Alan Carr and kick it to the ground. Anyway got a call last Tuesday that the doctor wants to see me again. My question is I am going to be told I have cancer. I used this message board 2 years ago as my Dad had stomach cancer and I found it to be great. So I find myself in the situation that 2 years and 1 day after I lost the greatest man in my life. I am going to be sitting in a consultants office waiting for results. They did a bioposy on the tues as well. I am guessing its the results of that. But any feedback comments would be greatly appreciated. For the record I am 40 behave like 20. Meet the love of my life 6 weeks before my Dad died and we were going to try for a child this year. Would love to hear from anybody who has a similar situation. Thanks and I hate this disease that has robbed so many people of those that they love. XXX      

Did you know that you can treat cancer using this simple treatment protocol? - We want to inform you about a new way to treat cancer using simple, cheap and non-toxic supplements. This treatment protocol only uses compounds from fruits and vegetables and is very potent. If you don't believe it then try it and if it doesn't work we pay you $100. If it does work you must pay us $100. All instructions must be followed for this treatment protocol to work. Please print this page. Flavonoid Cancer Treatment Protocol 1 Dissolve 500 mg ascorbic acid (vitamin C) in 0.5 L water in a bottle.2 Open up a capsule containing 500 mg Quercetin and sprinkle this in this water. Shake well.3 If everything goes well you will see a yellow solution. The mix is ready for consumption. Drink very slowly (take a sip). If there are any side effects then please report this to your doctor. Please be informed that tumor lysis syndrome may be a possible complication of cancer treatment including this one. Our medical disclaimer states that you are responsible for your actions. This treatment protocol is potent stuff, it's a form of chemotherapy. Doctor's supervision recommended. These cheap supplements can be bought from anywhere (vitamin stores or internet). You can also use supplements that have quercetin and ascorbic acid combined (don't forget to dissolve content in 0.5 L of water in a bottle). You don't have to use exactly 500 mg quercetin and 500 mg ascorbic acid, 250 mg quercetin and 700 mg ascorbic acid for example is possible as well. Combined with chemotherapy and radiation this treatment protocol works 80+ times better, because quercetin uses free radicals to kill cancer cells and chemotherapy+radiation delivers these free radicals. Please contact us to tell us about how well this cancer treatment protocol worked. Also report any side effects that you may have encountered. For this and all other remarks email: quercetinadvocacy@hotmail.com Copyright © Quercetin advocacy group (please support our advocacy work)

Endometrial clear cell cancer post-op treatment? - Dec 2010: My partner of 7 years has been diagnosed with FIGO Grade-III endometrial clear cell cancer following a complete diVinci vaginal hysterectomy removing her uterus with pT3a tumor, tubes, ovaries and 15 lymph nodes (Dissected 0 positive).   She is getting additional opinions on OBGYN prescribed Chemo and radiation, since no other symptoms of adenocarcinoma are presented or indications of metastases except pelvic washings which were positive in pathology for adenocarcinoma.   Because these evaluations are of endometrial clear cell presence in surgery pelvic washings only, with no matastases in 15 lymph nodes dissected during surgery, we are (initially) hesitant about rushing into 18 weeks of chemo/radiation.   We are waiting on additional confirmation of lymph node immunostain pathology to confirm the negative carcinoma indications. Can anyone recommend a OBGYN or Gynecologic pathology expert in Fairfax County northern Virginia for a consult to get a 2nd opinion on the prescribed post-op treatment plan before we begin a chemo and radiation treatment program? Has anyone else been through a similar diagnosis lately about adenocarcinoma discovered in pelvic washings Only during hysterectomy only as basis for post surgery chemo/radiation treatment?

granulosa cell tumor recurrent - Hi to everyone.  I am in my mid fifties.  I am excited to find this site.  Don't we all feel alone in this plight.  I wonder between us how many different things we have been told by our physicians.  I have traveled many, many miles for answers. I was diagnosed with GCT in 2002.  I had a large tumor removed which was encapsulated in my ovary.  I was advised I needed no follow-up treatment.  Three years later I had 20+ tumors.  I had surgery to remove the tumors and the omentum.  One year later I had surgery to removed a smaller number of tumors.  And now one year later I have at least one tumor.My treatments began after the second surgery and have included:  Lupron, Carboplatin/Taxol, and Femara.  I have also developed cardiac problems and believe the cardiac complications are related to the cancer treatments. I am an advocate for knowledge in our plight against GCT.  I have a deep knowledge of GCT.  I have researched this cancer relentlessly over the past two years.I don't know how to accomplish it, but we need to share every idea we come up with.  And, anyone who is diagnosed MUST get a second opinion.  I am living a pretty normal life with GCT.  I've been to some of the best doctors in the US, and some that were not so good.When researching GCT, it is just as difficult to get a straight answer.  How many times have you been told it grows slow, and the next person tells you it grows fast?  How many times have you been told your going to die from this and the next time you are told most people don't die from this?  Have you ever just wanted to have a regular cancer; the kind people care about?  Did you ever dream of turning on the TV or opening a magazine and there is a group of people doing an awareness campaign and a fund raiser for GRANULOSA CELL TUMOR? Has anyone told you to go on a diet and you'll be cured?  I could go on and on.Please respond.  I have never met anyone with GCT.  I have never corresponded with anyone with GCT.  We are all connected, yet we are as lonely as the Maytag Repairman! Sparks  I    

RE: Gynecologic cancers - medicinemanRx@live.ca Free cancer treatment?

hi risk HPV/normal pap with cancer? - I was diagnosed with High risk HPV and had a conoscopy  in the nineties...My question is if you can still have cancerous cells hiding up in the vagina even if you have normal paps?

HSIL CIN 3 - A month ago I got a call from my doctor telling me that I had an abnormal pap smear.  They had me come in and have a colposcopy and cervical biopsy.  The results came in yesterday and I was told that I have CIN 3 from 12 o'clock to seven o'clock on my cervix.  At the time of the biopsy the doctor seemed to think that the LEEP procedure would be enough.  AFter getting the results of the biopsy he now wants me to have a Cone Biopsy done.  I am scheduled for surgery next week, but have a consultation with him this Friday.  I want to know what kinds of questions I should be prepared with.  I am only 25 and want to be able to have children.  With this being said...what are the next steps that I should take? I saw a medical video on the procedure and it looks like they take almost half of the cervix out...is this what is going to happen to me?

I have free Wigs to donate - hello, I am finally finished with my treatments and I would like to donate my 2 wigs to anyone who wants them. One is colar bone length and the other is shoulder length. both are a redish brown color and are synthetic. I spent over $100 on them, just write to me and let me know it you want them. they are both average size.   Ashley

Good medicine... - I will successfully treat (CURE) any cancer, in 3 months, or far less, or give you your money back! Nobody makes better medicine than God. If you're not made of it, it can't fix you! Sincerely, David, Master Herbalist and Practitioner of Organic Oncology.

radiation therapy for GCT of the ovaries - Hi,  I know I asked this question before, but I need to know if this therapy worked for anyone and how big can the tumors be to have a good result.  I have read that the tumors can be only 1cm.  My tumors are bigger than that.  Mine are like 4cm by 6cm and 6cm by 8cm some smaller  My last ct scan some increased and some decreased in size.  Pretty big huh.  I'm currently on avastin and taxal.  one time a week for 3 weeks then off for 1 week, then start over again as maintenance.  I'm currently on a good diet no white bread no white potatoes no pasta, mostly green vegs and chicken and fish.  I use beta glucan and Co Q10 and flaxseed 3-6-9 with either cottage cheese or organic yoghurt.  (Budwig Protocol).   Ann

PARP Inhibitors in Ovarian Cancer - Some cell-based assay labs have explored the biology of PARP inhibitors, alone and in combination, in actual human tumor primary culture micro-speheroids (microclusters), in breast, ovarian and other cancers. In these investigations, the lab applies the functional profiling platform to understand how PARP inhibitors enhance the effects of drugs and drug combinations. As seen with PARP inhibitors, mutations work with other proteins. Genes do not operate alone within the cell but in an intricate network of interactions. To date, one lab has observed good activity for the PARP inhibitors as single agents in BRCA1 positive patients and in some triple negative patients. Work is ongoing with these BRCA1 positive patients as wells as other tumor types where the PARP inhibitors may prove useful in the future. The PARP inhibitors are turning out to be very useful. On April 3rd, Dr. Robert Nagourney, medical director at Rational Therapeutics and associate clinical professor of Pharmacology at the University of California, Irvine School of Medicine, will have a Poster Session at the 102nd Annual Meeting of the American Association for Cancer Research (AACR) in Orlando, Florida on the most recent findings on novel compounds that target two parallel pathways in cancer cells. These small molecules, Olaparib (AZD2281) and Iniparib (BSI-201), disrupt the signal that drives cancer cell survival and proliferation (cell growth). Cell function analysis of the mTOR/P13K and MEK/ERK inhibitors, BEZ235 and AZD6244, alone and in combination in human tumor primary culture micro-spheroids (microclusters): Exploration of horizontal pathway targeting. While the profiles of each drug alone are of interest, the profiles of the drugs in combination are better still. The phenomenon of cross-talk defines an escape mechanism whereby cancer cells blocked from one passage, find a second. When clinical therapists have the capacity to block more than one pathway, the cancer cell is trapped and often dies. This is what has been observed with these duel inhibitor combinations. What is interesting is the fact that the activities cut across tumor types. Melanomas, colon cancers and lung cancers seem to have similar propensities to drive along these paths. Once again, we find that cancer biology is non-linear. Moreover, cancers share pathways across tumor types, pathways that might not intuitively seem related. This is the beauty of cell-based functional profiling platform. It allows the exploration of drugs and combinations that most oncologists wouldn't think of. It is these counterintuitive explorations that will likely lead to meaningful advances. Functional profiling measures biological signals rather than DNA indicators, which plays an important role in cancer drug selection and is demonstrably greater and more compelling data currently generated from DNA analyses. The results of their investigation support the clinical relevance of targeting the MEK/ERK and PI3K/mTOR pathways and more importantly, suggest "dual" pathway inhibition (horizontal) to be a productive strategy for further clinical development. Disease specific profiles and sequence dependence are being explored and will be reported. Most solid tumors reveal complex interactions between signal pathways that cross talk at points of commonality. To examine the clinical potential of BEZ235 and AZD6244 - inhibitors of PI3K and MEK/ERK pathways - they applied cell function analysis of programmed cell death to tumor micro-spheroids (microclusters) isolated from 24 patients. Drugs were tested alone and in combination. According to researcher, Professor Alan Ashworth, director of the Breaktrhough Breast Cancer Research Centre in London, the BRCA1 and BRCA2 genes are involved in a repair pathway for double-strand DNA breaks that occur very close to each other. An elaborate mechanism called homologous recombination fixes some of these double-strand breaks, and BRCA2 and BRCA1 are critical for homologous recombination. PARP is a very active enzyme involved in the repair of single-strand breaks in DNA or modified bases. It binds to DNA damage and adds multiple sugar molecules to the DNA that act as a beacon to recruit other components of DNA repair. Emerging work on assays (PARP levels correlating with response to PARP inhibitors) have shown pretty good response with PARP inhibitors as single agents in BRCA1 positive patients and in some triple negative patients. There has been some results combining the PARP inhbitors with mustard alkylators, platins and drug combinations to optimize PARP inhibitor combinations. Source: Robert A. Nagourney, Paula Bernard, Federico Francisco, Ryan Wexler, Steve Evans, Rational Therapeutics, Long Beach, CA. Proceedings of AACR - Volume 52 - April 2011.

Vaginal Pre Cancer or Cancer - I had a long over due Pap test about a week or so ago.  Had symptoms of painful intercourse with bleeding and discharge which had just recently occured.  Pain was interminent and seemed only on the outside.  Radical hysterectomy when 44, now 55. Went to robotic GYN and she looked around and did Pap then prescribed topical estrogen gel and Vagifem.  I asked why but Doc Robot didn't have time.  Last Monday I got a call stating that the Pap showed pre cancer cells and I need to come in for a biopsy which I did the next day.  Of course I was freaking out.  After the procedure she said I had HPV which causes these types of cancers then left the room without allowing me time to ask questions. Do these symtoms just show up out of the blue.  No problem before however it had been quite sometime since my last sexual encounter (years).  Didn't she miss some steps along the way like a repeat Pap, then the scope thing and then a biopsy.  And how does she know that I have HPY; does that show up on a Pap. Is it possible to have pre cells and full blown cancer at the same time. What is the next thing that usually happens after a diagnosis of pre cancer. I need info as I cannot wait the two weeks for biopsy results.  Can the stress attribute to an increase in pain or does it move that fast. I hate doctors and would feel better talking to someone who has been thru this. So very afraid. Thanks, Anitalu 

Small Cell Cervical Cancer - Hi. I noticed Small Cell is not a category under the GYN Cancers. I wanted to start a discussion on this type of cancer. My sister was just diagnosed. Any long term survivors out there?

A simple SEED -   Hi all,  I know a lot of people are against alternative medicine but I just wanted to share with everyone a website that I found that offers some alternatives or additions to conventional medicine.  I am not telling anyone to stop going to the doctor but this is something I believe everyone should try.  Go to www.apricotsfromgod.com and read about how a simple apricot seed changed the lives of many, many people!  Please let me know what you all think and if anyone tries taking the seeds please let me know if they work for you! By the way I am sharing this on every discussion board because I believe it will help someone the way it helped my family!  

Budwig Protocol - Has anyone used the Budwig Protocol?  has it worked for you?  I have GTC of the ovaries late stage and need to know ASAP.  Ann

Could it be Vulvar Melanoma? - Hi to All.  Went to gyn for PAP last week and he found a dark triangular sized mark where the labia minora meet at the bottom (called the "fourchette").  The mark is between 1/4"-1/2" at its widest point.  I am scheduled for a punch biopsy the day after next to "rule out melanoma".  I noticed this mark there within the last year or so but thought nothing of it because it didn't hurt.  I just thought it was a vein or something.  I also have mild on again/off again itching above my clitoris which recently started.  (I recently had a bartholin's gland cyst removed (marsupialization) on 9/30/09 and had a LEEP done in 1991, at which time I was diagnosed with HPV).  I am petrified that I may have cancer.  Has anyone else out there ever had or know of someone who has had a similar problem and, if so, what was the outcome?? 

Uterine Leiomyosarcoma - If you are interested in meeting someone who is using natural treatments and lifestyle to strengthen the immune system to fight Uterine Leiomyosarcoma, please visit my blog: http://uterine-leiomyosarcoma.blogspot.com When I was diagnosed with ULMS, I couldn't find anything encouraging on the internet. (In fact, every time I looked I got depressed!) So after two years I decided to create a blog to share the wonderful things I have learned about empowering the body to heal itself.  Please come visit me and let me know what you think. :)

Breath Samples Needed to Train Dogs to Detect Cancer - Cancer cells emit different metabolic waste products than normal cells. Their presence in cancer patients exhaled breath, blood or urine is so great that they can be detected by a dog's keen sense of smell, even in the early stages of disease.We are training dogs to detect the bio-chemical traces of cancer the same way other dogs are trained to detect traces of explosives or drugs.We invite you to help us develop a new non-invasive screening method for the early detection of cancer. We would like to obtain samples of your exhaled breath using a simple non-invasive device for the purpose of training dogs to detect cancer. The collection of your exhaled breath sample and information should take only 10 minutes. We will mail breath sample kits with a prepaid return envelope to anywhere in North America.(Note: you will not be "sniffed" by the dogs directly. The dogs will sniff the breath samples you provide, at a different location.) Who Can Participate:You have been newly diagnosed with and have not yet begun treatment for cancer. You have been recently tested and have never been diagnosed with cancer.To volunteer, email us at info@cancerdogs.caFor more information, visit us at http://www.cancerdogs.ca

stage 1 adenocarcinoma - I've been diagnosed with Stage 1 cervical Adenocarcinoma.  The GYN/ONC wants to proceed with surgery and take out my cervix and uterus, along with the lymphnodes.  I'm 32, have not yet had children and really want to.  I want to  if this extreme step is necessary right now, or if I could try to have a baby first and then have the surgery.  Any thoughts?

Ovarian cancer diagnosis - Hi.....I am a 61 year old woman who was diagnosed with Stage 3C Ovarian cancer in Novemer 2010. I have since had an operation to remove both ovaries, which had gigantic tumors in them as well as my Fallopian tubes and my omentum. My uterus was left untouched as it had been shrunken consieerable since my two Caesarean sections years ago. The doctor said I had some cancer remaining in the Peritineum and lymph nodes. My inital CA-125 was around 290, but now is down to 21, as I have had three chemos and am supposed to have three more. I understand that the protocol is for six chemos minimum, but I  would like to stop at four, as I have had no nausea and no dad side effects. Is that an unwise decision? I hate  to have any more toxins run through my body.

Free Housecleaning For Women during Chemo - Here is a link to check out if you are, or a woman you know  is having chemo treatments. This is a lovely idea and a real gift to those in need. http://www.cleaningforareason.org/ I have never used this service, I am just passing it along for your information.

Anyone with GCT and have liver metastasis? - Hello, If you, or someone you know, have or has had GCT with mets to the liver, please contact me and tell me anything you know about treatment options. I am looking for as much information as I can lay my hands on.  I am not getting much help from the doctor that is covering for my surgeon this week.  I had to get my ct scan results while he is on a weeks vacation, right?   Any way, some of the best information I have received has come via this msg board.  Thank you one and all! Sincerely, Renee/Sunset5

Uterine Cancer Detected on Cervical Biopsy - I don't think I got all the correct medical language from my doctor, but here is the series of events so far: I am 41 years old. I have had 2 children and 1 miscarriage. I have never had an abnormal PAP smear or unusual gynecological symptoms. Last month, I had an abnormal PAP. I went back for colposcopy. Both the PAP and the biopsy after the colposcopy showed HSIL CIN II/III. Then while looking at the biopsy results, my doctor said there were uterine cancer cells detected - not the type of cells one would find on the cervix. Now he wants to do a cold knife conization to remove a cone shaped section of the cervix and then have further biopsy. But he is prepping me that I will most likely need a hysterectomy. I guess without the exact language on the biopsy, I don't know what type of uterine cancer would be detected through a cervical biopsy. Would it most likely be endometrial? If I do need a hysterectomy, how/when will I know if I need other treatment such as radiation or chemotherapy? Will the results of the cone biopsy determine what treatment is needed and if I should see a gynecological oncologist? Thanks for any advice or experiences you can offer. Best wishes, Anna

New to the 'C' word - Two days ago was told by my gyn that the biopsy from my labia is the 'C' word.  All I remember asking her was am I going to live.  Have spent some time doing research but nothing is sinking in yet.  I will be going to a clinic hopefully this week and from what I have found out about the gyn/oncologist, he seems to be very well qualified.  I don't have medical insurance and my doc said the clinic will help me.  Guess I am looking for a few women who can offer some insight into what I should expect and do.  I have a list of questions to ask the new doctor, however finding it difficult to stay focused or balanced.  The last few days have been a real emotional roller coaster.  I also hope the clinic will have some sort of a support group.   Am open to any replies.  Susan63